Article
Ezrin is essential for the entry of Japanese encephalitis virus into the human brain microvascular endothelial cells
1 Jan 2020
Abstract excerpt
Japanese encephalitis virus (JEV) remains the predominant cause of viral encephalitis worldwide. It reaches the central nervous system upon crossing the blood–brain barrier through pathogenic mechanisms that are not completely understood. Here, using a high-throughput siRNA screening assay combined with verification experiments, we found that JEV enters the primary human brain microvascular endothelial cells...
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