Article
A Third MLPH Variant Causing Coat Color Dilution in Dogs.
Genes - 10 Jun 2020
Van Buren Samantha L, Minor Katie M, Grahn Robert A, Mickelson James R, Grahn Jennifer C, Malvick Julia, Colangelo Jennifer R, Mueller Elisabeth, Kuehnlein Petra, Kehl Alexandra
Abstract excerpt
Altered melanosome transport in melanocytes, resulting from variants in the melanophilin (MLPH) gene, are associated with inherited forms of coat color dilution in many species. In dogs, the MLPH gene corresponds to the D locus and two variants, c.-22G > A (d1) and c.705G > C (d2), leading to the dilution of coat color, as described. Here, we describe the independent investigations of dogs whose coat color...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.