Article
Downregulation of B regulatory cells and upregulation of T helper 1 cells in children with Gaucher disease undergoing enzyme replacement therapy.
Immunologic research - 1 Apr 2020
Zahran Asmaa M, Youssef Mervat A M, Shafik Engy Adel, Zahran Zeinab Albadry M, El-Badawy Omnia, Abo Elgheet Amir M, Elsayh Khalid I
Abstract excerpt
Gaucher disease (GD) involves a broad spectrum of immunological cells, including T helper (Th) cells and regulatory B cells (Bregs), which function to resolve the immune response and inhibit excessive inflammation. This study aimed to explore T helper cells, B cells, and Bregs in GD children undergoing enzyme replacement therapy (ERT). Our study included 20 GD patients; six patients were categorized as type 1 and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.