Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic prediction of major depressive disorder.

Molecular psychiatry - 1 Sept 2021

Barbu Miruna C, Shen Xueyi, Walker Rosie M, Howard David M, Evans Kathryn L, Whalley Heather C, Porteous David J, Morris Stewart W, Deary Ian J, Zeng Yanni, Marioni Riccardo E, Clarke Toni-Kim, McIntosh Andrew M

Abstract excerpt

Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with major depressive disorder (MDD). Using penalised regression on genome-wide CpG methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 controls, could discriminate between cases...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Depressive Disorder, Major
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenomics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Multifactorial Inheritance

Source

Open in PubMed Open full text

Identifiers

PMID: 32523041
DOI: 10.1038/s41380-020-0808-3
PMCID: PMC8589651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic prediction of major depressive disorder.PMID 32523041Read ↗

A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparisonSemantic proximity Read ↗

Epigenetic prediction of complex traits and deathSemantic proximity Read ↗

DNA Methylation in Depression and Depressive-Like Phenotype: Biomarker or Target of Pharmacological Intervention?Semantic proximity Read ↗

DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responsesSemantic proximity Read ↗

Molecular studies of major depressive disorder: the epigenetic perspective.Semantic proximity Read ↗

DNA Methylation in Major Depressive Disorder.Semantic proximity Read ↗

Causes and consequences of major depressive disorder: An encompassing Mendelian randomization studySemantic proximity Read ↗

The genetic basis of major depressive disorder.Semantic proximity Read ↗

Polygenic prediction of major depressive disorder and related traits in African ancestries UK Biobank participants.Semantic proximity Read ↗

Sex-specific and multiomic integration enhance accuracy of peripheral blood biomarkers of major depressive disorderSemantic proximity Read ↗

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.Semantic proximity Read ↗

Advancing Depression Management Through Biomarker Discovery with a Focus on Genetic and Epigenetic Aspects: A Comprehensive Study on Neurobiological, Neuroendocrine, Metabolic, and Inflammatory PathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.