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Article

Transglycosidase activity of glycosynthase-type mutants of a fungal GH20 β-N-acetylhexosaminidase.

International journal of biological macromolecules - 15 Oct 2020

Kapešová Jana, Petrásková Lucie, Kulik Natalia, Straková Zuzana, Bojarová Pavla, Markošová Kristína, Rebroš Martin, Křen Vladimír, Slámová Kristýna

Abstract excerpt

β-N-Acetylhexosaminidases (CAZy GH20, EC 3.2.1.52) are exo-glycosidases specific for cleaving N-acetylglucosamine and N-acetylgalactosamine moieties of various substrates. The β-N-acetylhexosaminidase from the filamentous fungus Talaromyces flavus (TfHex), a model enzyme in this study, has a broad substrate flexibility and outstanding synthetic ability. We have designed and characterized seven glycosynthase-type...

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PMID: 32522540
DOI: 10.1016/j.ijbiomac.2020.05.273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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