Article
The Cadherin Protein Is Not Involved in Susceptibility to Bacillus thuringiensis Cry1Ab or Cry1Fa Toxins in Spodoptera frugiperda.
Toxins - 6 Jun 2020
Zhang Jianfeng, Jin Minghui, Yang Yanchao, Liu Leilei, Yang Yongbo, Gómez Isabel, Bravo Alejandra, Soberón Mario, Xiao Yutao, Liu Kaiyu
Abstract excerpt
It is well known that insect larval midgut cadherin protein serves as a receptor of Bacillus thuringiensis (Bt) crystal Cry1Ac or Cry1Ab toxins, since structural mutations and downregulation of cad gene expression are linked with resistance to Cry1Ac toxin in several lepidopteran insects. However, the role of Spodoptera frugiperda cadherin protein (SfCad) in the mode of action of Bt toxins remains elusive. Here,...
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