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Article

Synergistic resistance of Helicoverpa armigera to Bt toxins linked to cadherin and ABC transporters mutations.

Insect biochemistry and molecular biology - 1 Oct 2021

Zhang Dandan, Jin Minghui, Yang Yanchao, Zhang Jianfeng, Yang Yongbo, Liu Kaiyu, Soberón Mario, Bravo Alejandra, Xiao Yutao, Wu Kongming

Abstract excerpt

Resistance evolution of target pests reduces efficacy of Bacillus thuringiensis Cry toxins used in insect-pest control. Mutations in Cadherin (CAD) or ATP-binding cassette (ABC) transporters genes are linked to Cry resistance in different pests. Also, it has been shown that ABCC2 and CAD have synergistic interaction on Cry toxicity when co-express in cell lines, which we confirmed here by Helicoverpa armigera...

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Identifiers

PMID: 34363975
DOI: 10.1016/j.ibmb.2021.103635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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