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Prenatal exposure to pesticides and risk for holoprosencephaly: a case-control study

8 Jun 2020

Abstract excerpt

BACKGROUND: Pesticide exposure during susceptible windows and at certain doses are linked to numerous birth defects. Early experimental evidence suggests an association between active ingredients in pesticides and holoprosencephaly (HPE), the most common malformation of the forebrain in humans (1 in 250 embryos). No human studies to date have examined the association. This study investigated pesticides during...

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PMID: 32513280
DOI: 10.1186/s12940-020-00611-z

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