Article
Genetic and functional diversification of chemosensory pathway receptors in mosquito-borne filarial nematodes.
PLoS biology - 1 Jun 2020
Wheeler Nicolas J, Heimark Zachary W, Airs Paul M, Mann Alexis, Bartholomay Lyric C, Zamanian Mostafa
Abstract excerpt
Lymphatic filariasis (LF) afflicts over 60 million people worldwide and leads to severe pathological outcomes in chronic cases. The nematode parasites (Nematoda: Filarioidea) that cause LF require both arthropod (mosquito) intermediate hosts and mammalian definitive hosts for their propagation. The invasion and migration of filarial worms through host tissues are complex and critical to survival, yet little is...
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