Article
Association of variants in selected genes mediating host immune response with duration of Staphylococcus aureus bacteremia.
Genes and immunity - 1 Aug 2020
Carter Tonia C, Ye Zhan, Ivacic Lynn C, Budi Noah, Rose Warren E, Shukla Sanjay K
Abstract excerpt
Host genetic variation may be a contributing factor to variability in Staphylococcus aureus bacteremia duration. We assessed whether 28 single nucleotide polymorphisms (SNPs) in seven genes (TLR2, TLR4, TIRAP, IRAK4, TRAF6, NOD2, and CISH) that mediate host immune response were associated with S. aureus bacteremia duration. Subjects included 158 patients with short-term (≤4 days) and 44 with persistent (>4 days)...
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