Article
Refined carbohydrate-rich diet is associated with long-term risk of dementia and Alzheimer's disease in apolipoprotein E ε4 allele carriers.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jul 2020
Gentreau Mélissa, Chuy Virginie, Féart Catherine, Samieri Cécilia, Ritchie Karen, Raymond Michel, Berticat Claire, Artero Sylvaine
Abstract excerpt
INTRODUCTION: In animal models, refined carbohydrates (RF) worsen Alzheimer's disease (AD). However, the long-term effects of high RF intake on the risk of dementia and AD are poorly described in epidemiological studies. Moreover, the interaction between RF and the apolipoprotein E ε4 allele (APOE-ε4) is unknown. Our study investigated whether RF-rich diets are associated with the risk of dementia and AD....
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