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Article

Fat Distribution in Women Is Associated With Depot-Specific Transcriptomic Signatures and Chromatin Structure

8 Apr 2020

Abstract excerpt

BACKGROUND: Preferential accumulation of fat in the upper body (apple shape) is associated with higher risk of developing metabolic syndrome relative to lower body fat (pear shape). We previously discovered that chromatin openness partially defined the transcriptome of preadipocytes isolated from abdominal and gluteofemoral fat. However, the molecular mechanisms underlying interindividual variation in body shape...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32500109
DOI: 10.1210/jendso/bvaa042

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