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Article

Epigenetic regulation of diabetogenic adipose morphology

17 Apr 2019

Abstract excerpt

OBJECTIVE: Hypertrophic white adipose tissue (WAT) morphology is associated with insulin resistance and type 2 diabetes. The mechanisms governing hyperplastic versus hypertrophic WAT expansion are poorly understood. We assessed if epigenetic modifications in adipocytes are associated with hypertrophic adipose morphology. A subset of genes with differentially methylated CpG-sites (DMS) in the promoters was taken...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 31031182
DOI: 10.1016/j.molmet.2019.04.009

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