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Article

A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer

1 Feb 2011

Abstract excerpt

BACKGROUND: NET1, a RhoA guanine exchange factor, is up-regulated in gastric cancer (GC) tissue and drives the invasive phenotype of this disease. In this study, we aimed to determine the role of NET1 in GC by monitoring the proliferation, motility and invasion of GC cells in which NET1 has been stably knocked down. Additionally, we aimed to determine NET1-dependent transcriptomic events that occur in GC....

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PMID: 21284875
DOI: 10.1186/1471-2407-11-50

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