Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical applications of cell-free DNA-based liquid biopsy analysis

6 Sept 2025

Abstract excerpt

Liquid biopsies, particularly those involving circulating tumor DNA (ctDNA) from patient blood, have emerged as crucial and minimally invasive adjuncts to standard tissue-based testing. ctDNA testing enables the identification of actionable mutations for targeted therapy and can be routinely used when tissue samples are unavailable for genotyping. Compared to tissue-based testing, ctDNA testing has the advantages...

Topics

Join the communities discussing this publication.

Cancer Genomics and Diagnostics
Genetic factors in colorectal cancer
Single-cell and spatial transcriptomics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40915174
DOI: 10.1016/j.tranon.2025.102519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical applications of cell-free DNA-based liquid biopsy analysisPMID 40915174Read ↗

Liquid biopsies across the cancer care continuum.Semantic proximity Read ↗

Toward liquid biopsies in cancer treatment: application of circulating tumor DNASemantic proximity Read ↗

Liquid Biopsies beyond Mutation Calling: Genomic and Epigenomic Features of Cell-Free DNA in CancerSemantic proximity Read ↗

A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications.Semantic proximity Read ↗

Liquid Biopsy: Approaches to Dynamic Genotyping in CancerSemantic proximity Read ↗

Circulating tumor DNA: current challenges for clinical utility.Semantic proximity Read ↗

Genomics and Epigenomics Approaches for the Quantification of Circulating Tumor DNA in Liquid Biopsy: Relevance of a Multimodal StrategySemantic proximity Read ↗

Practical Considerations for the Use of Circulating Tumor DNA in the Treatment of Patients With Cancer: A Narrative Review.Semantic proximity Read ↗

Circulating Cell-Free DNA—Diagnostic and Prognostic Applications in Personalized Cancer TherapySemantic proximity Read ↗

Liquid biopsy: current technology and clinical applicationsSemantic proximity Read ↗

[Applications and limitations of liquid biopsy : Applications and methodological limitations of cell-free DNA analysis in tumor diagnostics].Semantic proximity Read ↗

Liquid Biopsy in the Clinical Management of CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.