Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selective capture of plasma cell-free tumor DNA on magnetic beads: a sensitive and versatile tool for liquid biopsy.

Cellular oncology (Dordrecht, Netherlands) - 1 Oct 2020

Kerachian Mohammad Amin, Azghandi Marjan, Javadmanesh Ali, Ghaffarzadegan Kamran, Mozaffari-Jovin Sina

Abstract excerpt

PURPOSE: Recently, 'solid tumor biopsies' have been challenged by the emergence of 'liquid biopsies', which are aimed at the isolation and detection of circulating cell-free tumor DNA (ctDNA) in body fluids. Here, we developed and optimized a method for selective capture of ctDNA on magnetic beads (SCC-MAG) for mutation detection in plasma of patients with colorectal cancer (CRC). METHODS: Blood and tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell-Free Nucleic Acids
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to DNA, Neoplasm

Share to Limit of Detection

Share to Liquid Biopsy

Share to Microspheres

Share to Proto-Oncogene Proteins p21(ras)

Source

Open in PubMed Open full text

Identifiers

PMID: 32495293
DOI: 10.1007/s13402-020-00536-2
PMCID: PMC12990742

Genes

MAG
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selective capture of plasma cell-free tumor DNA on magnetic beads: a sensitive and versatile tool for liquid biopsy.PMID 32495293Read ↗

NGS-Based Tumor-Informed Analysis of Circulating Tumor DNA.Semantic proximity Read ↗

Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients.Semantic proximity Read ↗

Solid-Phase Microextraction Enables Isolation of BRAF V600E Circulating Tumor DNA from Human Plasma for Detection with a Molecular Beacon Loop-Mediated Isothermal Amplification Assay.Semantic proximity Read ↗

Increased detection of circulating tumor DNA by short fragment enrichmentSemantic proximity Read ↗

High-fidelity target sequencing of individual molecules identified using barcode sequences: de novo detection and absolute quantitation of mutations in plasma cell-free DNA from cancer patients.Semantic proximity Read ↗

Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCRSemantic proximity Read ↗

NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patientsSemantic proximity Read ↗

Rapid Multiplex Strip Test for the Detection of Circulating Tumor DNA Mutations for Liquid Biopsy Applications.Semantic proximity Read ↗

Single-Tube, Switched Temperature Amplicon Barcoding for Multiplex Detection of Rare Mutations in Circulating Tumor DNA.Semantic proximity Read ↗

Automated DNA extraction using cellulose magnetic beads can improve EGFR point mutation detection with liquid biopsy by efficiently recovering short and long DNA fragmentsSemantic proximity Read ↗

Selective hybridization and capture of KRAS DNA from plasma and blood using ion-tagged oligonucleotide probes coupled to magnetic ionic liquids.Semantic proximity Read ↗

A nano-magnetic size selective cfDNA extraction platform for liquid biopsy with enhanced precision.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.