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Article

Host-Virus Arms Races Drive Elevated Adaptive Evolution in Viral Receptors.

Journal of virology - 30 Jul 2020

Wang Wenqiang, Zhao Huayao, Han Guan-Zhu

Abstract excerpt

Viral receptors are the cell surface proteins that are hijacked by viruses to initialize their infections. Viral receptors are subject to two conflicting directional forces, namely, negative selection due to functional constraints and positive selection due to host-virus arms races. It remains largely obscure whether negative pleiotropy limits the rate of adaptation in viral receptors. Here, we perform...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32493827
DOI: 10.1128/JVI.00684-20
PMCID: PMC7394895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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