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Fusions involving BCOR and CREBBP are rare events in infiltrating glioma

3 Jun 2020

Abstract excerpt

BCOR has been recognized as a recurrently altered gene in a subset of pediatric tumors of the central nervous system (CNS). Here, we describe a novel BCOR-CREBBP fusion event in a case of pediatric infiltrating astrocytoma and further probe the frequency of related fusion events in CNS tumors. We analyzed biopsy samples taken from a 15-year-old male with an aggressive, unresectable and multifocal infiltrating...

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PMID: 32493417
DOI: 10.1186/s40478-020-00951-4

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