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Article

Insulinemic Potential of Lifestyle Is Inversely Associated with Leukocyte Mitochondrial DNA Copy Number in US White Adults.

The Journal of nutrition - 1 Aug 2020

Yang Keming, Forman Michele R, Monahan Patrick O, Graham Brett H, Chan Andrew T, Zhang Xuehong, De Vivo Immaculata, Giovannucci Edward L, Tabung Fred K, Nan Hongmei

Abstract excerpt

BACKGROUND: Poor lifestyles have been linked to insulin insensitivity/hyperinsulinemia, which may contribute to downstream changes such as inflammation and oxidative damage and the development of chronic diseases. As a biomarker of intracellular oxidative stress, leukocyte mitochondrial DNA copy number (mtDNA-CN) has been related to lifestyle factors including diet and weight. No epidemiologic study has examined...

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Identifiers

PMID: 32492151
DOI: 10.1093/jn/nxaa146
PMCID: PMC7398789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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