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Article

Differential expression of miRNAs and their target genes: Exploring a new perspective of acquired aplastic anemia pathogenesis.

International journal of laboratory hematology - 1 Oct 2020

Srivastava Jyotika, Chaturvedi Chandra P, Rahman Khaliqur, Gupta Ruchi, Sharma Akhilesh, Chandra Dinesh, Singh Manish K, Gupta Anshul, Yadav Sanjeev, Nityanand Soniya

Abstract excerpt

INTRODUCTION: MicroRNAs (miRNAs) play a critical role in orchestrating T cell differentiation and activation and may thus play a vital role in acquired aplastic anemia (aAA). The study aimed to evaluate the differential expression of selected miRNAs and their relevant target genes in bone marrow samples of aAA patients. METHODS: Differential expression of 8 miRNAs viz; hsa-miR-126-3p, miR-145-5p, miR-155-5p,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32490599
DOI: 10.1111/ijlh.13245

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