Article
A homologous overexpression system to study roles of drug transporters in Candida glabrata.
FEMS yeast research - 1 Jun 2020
Kumari Sonam, Kumar Mohit, Khandelwal Nitesh Kumar, Pandey Ajay Kumar, Bhakt Priyanka, Kaur Rupinder, Prasad Rajendra, Gaur Naseem A
Abstract excerpt
Considering the relevance of drug transporters belonging to ABC and MFS superfamilies in pathogenic Candida species, there has always been a need to have an overexpression system where these membrane proteins for functional analysis could be expressed in a homologous background. We could address this unmet need by constructing a highly drug-susceptible Candida glabrata strain deleted in seven dominant ABC...
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