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Article

HIF1A expression correlates with increased tumor immune and stromal signatures and aggressive phenotypes in human cancers.

Cellular oncology (Dordrecht, Netherlands) - 1 Oct 2020

Chen Baotao, Li Lin, Li Mengyuan, Wang Xiaosheng

Abstract excerpt

BACKGROUND: Although many studies have revealed essential roles of HIF1A (hypoxia inducible factor 1 subunit alpha) in regulating various pathways associated with cancer development, a systematic investigation of associations of HIF1A expression with tumor immunity, the tumor microenvironment and other tumor phenotypes in pan-cancer is lacking. METHODS: Using cancer genomics datasets of 10 cancer cohorts from the...

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Source

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Identifiers

PMID: 32488852
DOI: 10.1007/s13402-020-00534-4
PMCID: PMC12990741

Genes

HIF1A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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