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Article

A pan-cancer analysis of RNASEH1, a potential regulator of the tumor microenvironment.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Aug 2023

Yi Chen, Yang Jun, Zhang Ting, Xie Shien, Li Wentao, Qin Liu, Chen Dongjuan

Abstract excerpt

BACKGROUND: RNASEH1 (Ribonuclease H1) encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and acts in DNA replication and repair. Although there are many studies on RNASEH1, the research of RNASEH1 in cancers is still insufficient. Therefore, in order to clarify the physiological mechanism of RNASEH1 in tumor cells, we evaluated the role of RNASEH1 by combining The Cancer Genome Atlas...

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PMID: 37022517
DOI: 10.1007/s12094-023-03142-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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