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GSTs polymorphisms are associated with epigenetic silencing of CDKN2A gene in esophageal squamous cell carcinoma.

Environmental science and pollution research international - 1 Sept 2020

Forghanifard Mohammad Mahdi, Aarabi Azadeh, Nasiri Aghdam Maryam, Memar Bahram, Hasanzadeh Khayat Mohammad, Dadkhah Ezzat, Abbaszadegan Mohammad Reza

Abstract excerpt

Esophageal cancer is the eighth most common cancer and the sixth most frequent cause of cancer mortality worldwide. Exposure to polycyclic aromatic hydrocarbons formed by incomplete combustion of organic matter is an important risk factor. Genetic polymorphisms in genes encoding PAH-metabolizing enzymes like glutathione S-transferases (GSTM1, GSTP1, GSTT1) which conjugate glutathione to PAHs for reduction of...

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PMID: 32488710
DOI: 10.1007/s11356-020-09408-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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