Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

cGMP Signaling in Cardiovascular Diseases: Linking Genotype and Phenotype.

Journal of cardiovascular pharmacology - 1 Jun 2020

Dang Tan An, Schunkert Heribert, Kessler Thorsten

Abstract excerpt

Cyclic guanosine 3',5'-monophosphate (cGMP) is the key second messenger molecule in nitric oxide signaling. Its rapid generation and fate, but also its role in mediating acute cellular functions has been extensively studied. In the past years, genetic studies suggested an important role for cGMP in affecting the risk of chronic cardiovascular diseases, for example, coronary artery disease and myocardial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Agents
Share to Cardiovascular Diseases
Share to Cardiovascular System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic GMP

Share to Genetic Variation

Share to Nitric Oxide

Share to Phenotype

Share to Second Messenger Systems

Source

Identifiers

PMID: 32487847
DOI: 10.1097/FJC.0000000000000744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

cGMP Signaling in Cardiovascular Diseases: Linking Genotype and Phenotype.PMID 32487847Read ↗

Role of sGC-dependent NO signalling and myocardial infarction risk.Semantic proximity Read ↗

Genetic alterations in the NO-cGMP pathway and cardiovascular risk.Semantic proximity Read ↗

Genetic modification of hypertension by sGCα1.Semantic proximity Read ↗

Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.Semantic proximity Read ↗

Overview of PDEs and their regulation.Semantic proximity Read ↗

Regulators of G protein signaling in cardiovascular function during pregnancy.Semantic proximity Read ↗

Nitric oxide synthases in the pathogenesis of cardiovascular diseaseSemantic proximity Read ↗

Prognostic Implications of Genetics in Cardiovascular Disease.Semantic proximity Read ↗

Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus.Semantic proximity Read ↗

G proteins, hypertension, and coronary heart disease--novel findings and hypotheses.Semantic proximity Read ↗

Clinical and Molecular Genetics of the Phosphodiesterases (PDEs)Semantic proximity Read ↗

Signalling by cGMP-dependent protein kinases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.