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Article

Signalling by cGMP-dependent protein kinases.

Molecular and cellular biochemistry - 1 Jan 2000

Vaandrager A B, de Jonge H R

Abstract excerpt

The second messenger cGMP is a major intracellular mediator of the vaso-active agents nitric oxide and natriuretic peptides. The principal targets of cGMP are (i) phosphodiesterases, resulting in interference with the cAMP-signalling pathway, (ii) cGMP-gated cation channels, and (iii) cGMP-dependent protein kinases (cGKs). Only two mammalian isotypes of cGK have been described so far: type I cGK, consisting of an...

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PMID: 8739225
DOI: 10.1007/BF00227877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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