Article
The methylation status of TNF-α and SOCS3 promoters and the regulation of these gene expressions in patients with Behçet's disease.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jul 2020
Aziz Shiva Gholizadeh-Ghaleh, Aziz Sara Gholizadeh-Ghaleh, Khabbazi Alireza, Alipour Shahriar
Abstract excerpt
Introduction: The aim of this study was to evaluate the methylation status of TNF-α and SOCS3 promoters in patients with BD and compare them with a healthy group.Method: This was a case-control study, in which 47 subjects with BD and 61 individuals as the control participated. Blood samples were collected from all the participants. Then, PBMCs were isolated using the Ficoll method and methylation of considered...
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