Article
Latent Class Trajectory Modeling of 2-Component Disease Activity Score in 28 Joints Identifies Multiple Rheumatoid Arthritis Phenotypes of Response to Biologic Disease-Modifying Antirheumatic Drugs.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Oct 2020
Dagliati Arianna, Plant Darren, Nair Nisha, Jani Meghna, Amico Beatrice, Peek Niels, Morgan Ann W, Isaacs John, Wilson Anthony G, Hyrich Kimme L, Geifman Nophar, Barton Anne
Abstract excerpt
OBJECTIVE: To determine whether using a reweighted disease activity score that better reflects joint synovitis, i.e., the 2-component Disease Activity Score in 28 joints (DAS28) (based on swollen joint count and C-reactive protein level), produces more clinically relevant treatment outcome trajectories compared to the standard 4-component DAS28. METHODS: Latent class mixed modeling of response to biologic...
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