Article
Psoriatic arthritis phenotype clusters and their association with treatment response: a real-world longitudinal cohort study from the psoriatic arthritis research consortium.
Annals of the rheumatic diseases - 1 Feb 2025
Karmacharya Paras, Crofford Leslie J, Byrne Daniel W, Stephens-Shields Alisa, Husni M Elaine, Scher Jose U, Craig Ethan, Fitzsimmons Robert, Reddy Soumya M, Magrey Marina N, Walsh Jessica A, Ogdie Alexis
Abstract excerpt
OBJECTIVES: To identify phenotype clusters and their trajectories in psoriatic arthritis (PsA) and examine the association of the clusters with treatment response in a real-world setting. METHODS: In the multicentre PsA Research Consortium (PARC) study, we applied factor analysis of mixed data to reduce dimensionality and collinearity, followed by hierarchical clustering on principal components. We then evaluated...
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