Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Data-Driven Patient Clustering and Differential Clinical Outcomes in the Brigham and Women's Rheumatoid Arthritis Sequential Study Registry.

Arthritis care & research - 1 Apr 2021

Curtis Jeffrey R, Weinblatt Michael, Saag Kenneth, Bykerk Vivian P, Furst Daniel E, Fiore Stefano, St John Gregory, Kimura Toshio, Zheng Shen, Bingham Clifton O, Wright Grace, Bergman Martin, Nola Kamala, Charles-Schoeman Christina, Shadick Nancy

Abstract excerpt

OBJECTIVE: To use unbiased, data-driven, principal component (PC) and cluster analysis to identify patient phenotypes of rheumatoid arthritis (RA) that might exhibit distinct trajectories of disease progression, response to treatment, and risk for adverse events. METHODS: Patient demographic, socioeconomic, health, and disease characteristics recorded at entry into a large, single-center, prospective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Boston

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Data Mining

Share to Health Status

Share to Incidence

Share to Principal Component Analysis

Share to Registries

Share to Socioeconomic Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 33002337
DOI: 10.1002/acr.24471
PMCID: PMC8048846

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Data-Driven Patient Clustering and Differential Clinical Outcomes in the Brigham and Women's Rheumatoid Arthritis Sequential Study Registry.PMID 33002337Read ↗

Clinical phenotype with high risk for initiation of biologic therapy in rheumatoid arthritis: a data-driven cluster analysis.Semantic proximity Read ↗

Can alternative means of phenotyping rheumatoid arthritis reduce its apparent heterogeneity? A comparison of three disease activity classifications with DAS28.Semantic proximity Read ↗

Exploratory Multi-Omics Profiling of Rheumatoid Arthritis HeterogeneitySemantic proximity Read ↗

Multimorbidity phenotypes in ankylosing spondylitis and their association with disease activity and functional impairment: Data from the prospective study of outcomes in ankylosing spondylitis cohort.Semantic proximity Read ↗

Using genetic and clinical data to understand response to disease-modifying anti-rheumatic drug therapy: data from the Brigham and Women's Hospital Rheumatoid Arthritis Sequential Study.Semantic proximity Read ↗

Location and amount of joint involvement differentiates rheumatoid arthritis into different clinical subsetsSemantic proximity Read ↗

Latent Class Trajectory Modeling of 2-Component Disease Activity Score in 28 Joints Identifies Multiple Rheumatoid Arthritis Phenotypes of Response to Biologic Disease-Modifying Antirheumatic Drugs.Semantic proximity Read ↗

Plasma protein prioritisation in rheumatoid arthritis reveals druggable targets and shared biology with cardiovascular diseasesSemantic proximity Read ↗

Patterns of comorbidity and their impact on axial spondyloarthritisSemantic proximity Read ↗

Clinical-psychosocial archetypes predict short-term outcomes in inflammatory arthritis: an unsupervised segmentation study.Semantic proximity Read ↗

Disease progression and clinical outcomes in latent osteoarthritis phenotypes: Data from the Osteoarthritis InitiativeSemantic proximity Read ↗

Disease activity drives transcriptomic heterogeneity in early untreated rheumatoid synovitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.