Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy.

International journal of cancer - 15 Nov 2020

Haakensen Vilde D, Khadse Anand, Sandhu Vandana, Halvorsen Ann Rita, Solberg Steinar K, Jørgensen Lars H, Brustugun Odd Terje, Kure Elin H, Helland Åslaug

Abstract excerpt

Personalised cancer treatment depends on identification of therapeutically relevant biological subgroups of patients for assessing effect of treatment and to discover new therapeutic options. By analyses in heterogeneous patient populations, the effects may be lost in noise. Squamous cell carcinoma of the lung is a major killer worldwide. Despite recent advances, mortality is high and response to therapies varies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

Share to Gene Amplification

Share to Gene Dosage

Share to Precision Medicine

Share to Survivin

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 32468587
DOI: 10.1002/ijc.33121
PMCID: PMC7540694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy.PMID 32468587Read ↗

BIRC5 as a Potential Biomarker and Therapeutic Target for Lung Adenocarcinoma: A Comprehensive Bioinformatics AnalysisSemantic proximity Read ↗

Comprehensive genomic characterization of squamous cell lung cancers.Semantic proximity Read ↗

Transcriptome‐level discovery of survival‐associated biomarkers and therapy targets in non‐small‐cell lung cancerSemantic proximity Read ↗

Integrative analysis of TP53 mutations in lung adenocarcinoma for immunotherapies and prognosis.Semantic proximity Read ↗

Impact of genetic alterations on outcomes of patients with stage I nonsmall cell lung cancer: An analysis of the cancer genome atlas data.Semantic proximity Read ↗

Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer.Semantic proximity Read ↗

High tumor mutation burden predicts favorable outcome among patients with aggressive histological subtypes of lung adenocarcinoma: A population-based single-institution study.Semantic proximity Read ↗

Interrogating the Precancerous Evolution of Pathway Dysfunction in Lung Squamous Cell Carcinoma Using XTABLESemantic proximity Read ↗

Usefulness of predictive tests for cancer treatment.Semantic proximity Read ↗

Comprehensive transcriptome, miRNA and kinome profiling and its clinical translation for personalized lung cancer therapySemantic proximity Read ↗

Significance of TP53 Mutation in Cellular Process and Disease Progression in Lung Adenocarcinoma.Semantic proximity Read ↗

Clinical applications of The Cancer Genome Atlas project (TCGA) for squamous cell lung carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.