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Familial Hypercholesterolemia and the Founder Effect Among Franco-Americans: A Brief History and Call to Action

24 Jan 2020

Abstract excerpt

Familial hypercholesterolemia (FH) is an inherited disorder characterized by chronically elevated low-density lipoprotein cholesterol levels and an increased risk of premature atherosclerotic cardiovascular disease. FH has been shown to disproportionately affect French Canadians and other ethnic populations due to the presence of a founder effect characterized by reduced genetic diversity resulting from...

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PMID: 32462130
DOI: 10.1016/j.cjco.2020.01.003

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