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Article

Familial hypercholesterolemia in French-Canadians: taking advantage of the presence of a "founder effect".

The American journal of cardiology - 30 Sept 1993

Davignon J, Roy M

Abstract excerpt

The frequency of familial hypercholesterolemia (FH) in the Province of Quebec is twice that observed in most population samples. In the French-Canadian population, 5 mutations in the low density lipoprotein (LDL) receptor gene account for 76% of FH cases diagnosed using clinical and biochemical c...

Topics

Consanguinity
France
Humans
Hyperlipoproteinemia Type II
Mutation
Pedigree
Quebec
Receptors, LDL

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8213499
DOI: 10.1016/0002-9149(93)90003-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8213499-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Familial hypercholesterolemia in French-Canadians: taking advantage of the presence of a "founder effect".PMID 8213499Read ↗

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