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Article

Genetic susceptibility to heart disease in Canada: lessons from patients with familial hypercholesterolemia.

Genome - 1 Nov 2006

Hegele Robert A

Abstract excerpt

Much of the recent progress in treating patients with heart disease due to narrowed coronary arteries has resulted from studying disease evolution in patients with rare monogenic forms of disease. For instance, autosomal dominant familial hypercholesterolemia (FH, MIM (Mendelian Inheritance in Man) 143890) typically results from heterozygous mutations in LDLR encoding the low-density lipoprotein (LDL) receptor....

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Identifiers

PMID: 17426749
DOI: 10.1139/g06-147

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LDLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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