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Adenine DNA methylation, 3D genome organization, and gene expression in the parasite Trichomonas vaginalis

27 May 2020

Abstract excerpt

Trichomonas vaginalis is a common sexually transmitted parasite that colonizes the human urogenital tract causing infections that range from asymptomatic to highly inflammatory. Recent works have highlighted the importance of histone modifications in the regulation of transcription and parasite pathogenesis. However, the nature of DNA methylation in the parasite remains unexplored. Using a combination of...

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PMID: 32461362
DOI: 10.1073/pnas.1917286117

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