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Variants in HSD11B1 gene modulate susceptibility to diabetes kidney disease and to insulin resistance in type 1 diabetes.

Diabetes/metabolism research and reviews - 1 Jan 2021

Mori Rosana Cristina, Santos-Bezerra Daniele Pereira, Pelaes Tatiana Souza, Admoni Sharon Nina, Perez Ricardo Vessoni, Monteiro Maria Beatriz, Machado Cleide Guimarães, Queiroz Marcia Silva, Machado Ubiratan Fabres, Correa-Giannella Maria Lúcia

Abstract excerpt

BACKGROUND AND AIM: 11β-Hydroxysteroid dehydrogenase 1 has been implicated in insulin resistance (IR) in the setting of metabolic disorders, and single nucleotide polymorphisms (SNPs) in its encoding gene (HSD11B1) have been associated with type 2 diabetes and metabolic syndrome. In type 1 diabetes (T1D), IR has been related to the development of chronic complications. We investigated the association of HSD11B1...

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Share to Adrenal Hormones and Disorders
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Share to Hormonal Regulation and Hypertension

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Share to Paraoxonase enzyme and polymorphisms

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Identifiers

PMID: 32453474
DOI: 10.1002/dmrr.3352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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