Aquaporin 11 variant associates with kidney disease in type 2 diabetic patients.

doi:10.1152/ajprenal.00295.2015

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Article

Aquaporin 11 variant associates with kidney disease in type 2 diabetic patients.

American journal of physiology. Renal physiology - 1 Mar 2016

Choma David P, Vanacore Roberto, Naylor Helen, Zimmerman Ian A, Pavlichenko Andrei, Pavlichenko Artyom, Foye Liberty, Carbone David P, Harris Raymond C, Dikov Mikhail M, Tchekneva Elena E

Abstract excerpt

Kidney disease, a common complication of diabetes, associates with poor prognosis. Our previous animal model studies linked aquaporin (AQP)11 to acute kidney injury, hyperglycemia-induced renal impairment, and kidney disease in diabetes. Here, we report the AQP11 rs2276415 variant as a genetic factor placing type 2 diabetic patients at greater risk for the development of kidney disease. We performed two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26719361
DOI: 10.1152/ajprenal.00295.2015
PMCID: PMC4773830

Genes

AQP11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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