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Article

Integrated case-control and somatic-germline interaction analyses of soft-tissue sarcoma.

Journal of medical genetics - 1 Mar 2021

Hu Fulan, Yu Yao, Chen Jiun-Sheng, Hu Hao, Scheet Paul, Huff Chad D

Abstract excerpt

PURPOSE: The contribution of rare genetic variation in the development of soft-tissue sarcoma (STS) remains underexplored. To address this gap, we conducted a whole-exome case-control and somatic-germline interaction study to identify and characterise STS susceptible genes. METHODS: The study involved 219 STS cases from The Cancer Genome Atlas and 3507 controls. All cases and controls were matched genetically...

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Identifiers

PMID: 32447321
DOI: 10.1136/jmedgenet-2019-106814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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