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Article

Pure high-grade papillary urothelial bladder cancer: a luminal-like subgroup with potential for targeted therapy.

Cellular oncology (Dordrecht, Netherlands) - 1 Oct 2020

Schnitzler Tician, Ortiz-Brüchle Nadina, Schneider Ursula, Lurje Isabella, Guricova Karolina, Buchner Alexander, Schulz Gerald Bastian, Heidenreich Axel, Gaisa Nadine Therese, Knüchel Ruth, Garczyk Stefan

Abstract excerpt

PURPOSE: Non-invasive high-grade (HG) bladder cancer is a heterogeneous disease that is characterized insufficiently. First-line Bacillus Calmette-Guérin instillation fails in a substantial amount of cases and alternative bladder-preserving treatments are limited, underlining the need to promote a further molecular understanding of non-invasive HG lesions. Here, we characterized pure HG papillary urothelial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32445084
DOI: 10.1007/s13402-020-00524-6
PMCID: PMC7581583

Genes

ERBB2
FGFR3
ESR2
GATA3
KRT14
KRT20
KRT5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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