Article
Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use.
EBioMedicine - 1 Oct 2016
Dadhania Vipulkumar, Zhang Miao, Zhang Li, Bondaruk Jolanta, Majewski Tadeusz, Siefker-Radtke Arlene, Guo Charles C, Dinney Colin, Cogdell David E, Zhang Shizhen, Lee Sangkyou, Lee June G, Weinstein John N, Baggerly Keith, McConkey David, Czerniak Bogdan
Abstract excerpt
BACKGROUND: It has been suggested that bladder cancer can be divided into two molecular subtypes referred to as luminal and basal with distinct clinical behaviors and sensitivities to chemotherapy. We aimed to validate these subtypes in several clinical cohorts and identify signature immunohistochemical markers that would permit simple and cost-effective classification of the disease in primary care centers....
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