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Gut epithelial impairment, microbial translocation and immune system activation in inflammatory bowel disease–associated spondyloarthritis

13 Mar 2020

Abstract excerpt

OBJECTIVES: Gut microbiota has been widely reported to be involved in systemic inflammation through microbial translocation and T cell activation in several diseases. In this work we aimed to investigate bacterial infiltration and epithelial impairment in the gut of patients with IBD-associated SpA (SpA-IBD), as well as the relationship of microbial translocation with immune system activation and their putative...

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Share to Autoimmune and Inflammatory Disorders Research
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PMID: 32442267
DOI: 10.1093/rheumatology/keaa164

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