Article
Atrial Tissue Pro-Fibrotic M2 Macrophage Marker CD163+, Gene Expression of Procollagen and B-Type Natriuretic Peptide.
Journal of the American Heart Association - 2 Jun 2020
Watson Chris J, Glezeva Nadezhda, Horgan Stephen, Gallagher Joe, Phelan Dermot, McDonald Ken, Tolan Michael, Baugh John, Collier Patrick, Ledwidge Mark
Abstract excerpt
Background Atrial tissue fibrosis is linked to inflammatory cells, yet is incompletely understood. A growing body of literature associates peripheral blood levels of the antifibrotic hormone BNP (B-type natriuretic peptide) with atrial fibrillation (AF). We investigated the relationship between pro-fibrotic tissue M2 macrophage marker Cluster of Differentiation (CD)163+, atrial procollagen expression, and BNP...
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