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Genomic and phenotypic characterization of plasmid-mediated extensively drug-resistant Salmonella Typhi from Lahore Pakistan carrying IncY IncQ1 and IncC replicons.

Scientific reports - 16 Mar 2026

Jamil Iqra, Rehman Asad Ur, Rehman Muhammad Fayyaz Ur, Rasheed Farhan

Abstract excerpt

Antimicrobial resistance and emergence of MDR and XDR Salmonella enterica subsp. enterica serovar Typhi is a major threat in Pakistan. Failure of treatment with conventional antibiotics leads to importance of exploring alternative treatment plan. Therefore, this study aimed to check the resistance patterns and delineate the molecular basis of resistance among clinical isolates of S. typhi. 384 clinical isolates...

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Drug Resistance, Multiple, Bacterial
Genome, Bacterial
Microbial Sensitivity Tests
Pakistan
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Salmonella typhi

Whole Genome Sequencing

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Open in PubMed Open full text

Identifiers

PMID: 41839908
DOI: 10.1038/s41598-026-37560-5
PMCID: PMC13121732

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C2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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