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Article

Population phenomena inflate genetic associations of complex social traits.

Science advances - 1 Apr 2020

Morris Tim T, Davies Neil M, Hemani Gibran, Smith George Davey

Abstract excerpt

Heritability, genetic correlation, and genetic associations estimated from samples of unrelated individuals are often perceived as confirmation that genotype causes the phenotype(s). However, these estimates can arise from indirect mechanisms due to population phenomena including population stratification, dynastic effects, and assortative mating. We introduce these, describe how they can bias or inflate...

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PMID: 32426451
DOI: 10.1126/sciadv.aay0328
PMCID: PMC7159920

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Source receipt: pubmed, retrieved 7 Sept 2026.

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