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Article

Genetic nature or genetic nurture? Introducing social genetic parameters to quantify bias in polygenic score analyses.

Biodemography and social biology - 1 Jan 2000

Trejo Sam, Domingue Benjamin W

Abstract excerpt

Results from a genome-wide association study (GWAS) can be used to generate a polygenic score (PGS), an individual-level measure summarizing identified genetic influence on a trait dispersed across the genome. For complex, behavioral traits, the association between an individual's PGS and their phenotype may contain bias (from geographic, ancestral, and/or socioeconomic confounding) alongside the causal effect of...

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Identifiers

PMID: 31852332
DOI: 10.1080/19485565.2019.1681257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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