Article
Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.
Scientific reports - 15 May 2020
Vessies D C L, Greuter M J E, van Rooijen K L, Linders T C, Lanfermeijer M, Ramkisoensing K L, Meijer G A, Koopman M, Coupé V M H, Vink G R, Fijneman R J A, van den Broek D
Abstract excerpt
Multiple platforms are commercially available for the detection of circulating cell-free tumour DNA (ctDNA) from liquid biopsies. Since platforms have different input and output variables, deciding what platform to use for a given clinical or research question can be daunting. This study aimed to provide insight in platform selection criteria by comparing four commercial platforms that detect KRAS ctDNA hotspot...
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