Article
Impact of Extracellular Matrix Components to Renal Cell Carcinoma Behavior
28 Apr 2020
Abstract excerpt
Renal cell carcinoma (RCC) represents the main renal tumors and are highly metastatic. They are heterogeneous tumors and are subdivided in 12 different subtypes where clear cell RCC (ccRCC) represents the main subtype. Tumor extracellular matrix (ECM) is composed, in RCC, mainly of different fibrillar collagens, fibronectin and components of the basement membrane such as laminin, collagen IV and heparan sulfate...
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