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Article

Minding the gap in HIV host genetics: opportunities and challenges.

Human genetics - 1 Jun 2020

Gingras Shanelle N, Tang David, Tuff Jeffrey, McLaren Paul J

Abstract excerpt

Genome-wide association studies (GWAS) have been successful in identifying and confirming novel genetic variants that are associated with diverse HIV phenotypes. However, these studies have predominantly focused on European cohorts. HLA molecules have been consistently associated with HIV outcomes, some of which have been found to be population specific, underscoring the need for diversity in GWAS. Recently,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32409920
DOI: 10.1007/s00439-020-02177-9
PMCID: PMC7272494

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