Article
Interaction of thrombophilic SNPs in patients with unexplained infertility-multifactor dimensionality reduction (MDR) model analysis.
Journal of assisted reproduction and genetics - 1 Jun 2020
Milenkovic Jelena, Milojkovic Maja, Mitic Dejan, Stoimenov Tatjana Jevtovic, Smelcerovic Zaklina, Stojanovic Dijana, Vujic Stevan, Bojanic Novica
Abstract excerpt
PURPOSE: Our aim was to evaluate the frequency and SNP-SNP interactions between factor V Leiden (FVL) G1691A, prothrombin G20210A mutation, and C677T MTHFR and PAI-1 4G/5G gene polymorphisms in female IVF patients with unexplained infertility (UI) by using a multifactor dimensionality reduction (MDR) model analysis. METHODS: A total of 225 subjects were enrolled in the study. There were 105 females in UI group...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
