Article
Prefoldins contribute to maintaining the levels of the spliceosome LSM2-8 complex through Hsp90 in Arabidopsis.
Nucleic acids research - 19 Jun 2020
Esteve-Bruna David, Carrasco-López Cristian, Blanco-Touriñán Noel, Iserte Javier, Calleja-Cabrera Julián, Perea-Resa Carlos, Úrbez Cristina, Carrasco Pedro, Yanovsky Marcelo J, Blázquez Miguel A, Salinas Julio, Alabadí David
Abstract excerpt
Although originally identified as the components of the complex aiding the cytosolic chaperonin CCT in the folding of actins and tubulins in the cytosol, prefoldins (PFDs) are emerging as novel regulators influencing gene expression in the nucleus. Work conducted mainly in yeast and animals showed that PFDs act as transcriptional regulators and participate in the nuclear proteostasis. To investigate new functions...
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